![]() ![]() For the Xpert Xpress test, at 5%, 10%, and 20% prevalence, PPV is 65%, 80%, and 90%, respectively, with 100% specificity. This means that with 10% prevalence, if 1,000 people were tested, there would be 73 true-positives, three false-positives, 897 true-negatives, and 27 false-negatives. In a symptomatic population at 5%, 10%, and 20% prevalence, the ID NOW test PPV is 93%, 96%, and 98%, respectively, with a slight decrease in NPV (98.6%, 97.1%, and 93.6%, respectively). The Xpert Xpress test had a sensitivity and specificity of 100% (95% CI, 88.1% to 100%) and 97.2% (95% CI, 89.4% to 99.3%), respectively (two studies, 100 samples, 29 cases). ![]() When used in accordance with the manufacturer's instructions, ID NOW had a sensitivity and specificity of 73.0% (95% CI, 66.8% to 78.4%) and 99.7% (95% CI, 98.7% to 99.9%), respectively (four studies, 812 samples, 222 cases). The two most studied tests were the ID NOW COVID-19 test (Abbott) and the Xpert Xpress SARS-CoV-2 test. ![]() These tests work similarly to traditional PCR assays by amplifying RNA, but they are automated, require less handling and expertise to process, and typically produce results faster than traditional PCR tests. Other studies in the review examined the performance of rapid molecular tests for diagnosing SARS-CoV-2 infection. ![]()
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